I lost a lot of WIPs on my PC, references, emulators, and a plenty of stuff by mistake, the good thing is that I can also start refreshing things despite the mess, while it's good to organize things.
I really messed up when I had to format a new pendrive due to fear of having a virus, but still a mess since the formatting "deleted" most files, but thankfully I am working on recovering the lost files, without a bunch of my stuff might be "lost medias" by my fault